Niacet Monochloroacetic Acid (MCAA)

Monochloroacetic acid, also referred to as MCAA, is used as a versatile intermediate in the production of chemicals such as:

  • Carboxymethyl cellulose
  • 2-methyl-4-Chlorophenoxy
  • 2,4-dichloro phenoxy
  • Acetic acid (MCPA)
  • Acetic acid (2,4D)
  • Synthetic caffeine
  • Ethylchloroacetate
  • Sarcosine
  • Glycine
  • Thioglycolic acid

MCAA Applications

The main field of application of monochloroacetic acid is the manufacture of carboxymethylcellulose, which is used in the manufacture of adhesives, detergents, finishing agents for textile, leather and paper industries, and drilling muds for energy production.

Monochloroacetic acid is also an important intermediate for the manufacture of herbicides such as 2 .4-dichlorophenoxyacetic acid (2.4-D),2.4-5-trichlorophenoxyacetic acid (2.4.5-T) and 2-methyl-4-chlorophenoxyacetic acid (MCPA).

Thioglycolic acid, an important derivative of monochloroacetate, is used for the manufacture of stabilizers for polyvinyl chloride and of permanent hair waving preparations.

Monochloroacetic acid can be used as a building block for a number of further reactions besides those typical of monochloroacetic acids,
such as:

  • Alcohols– To form alkoxyacetic acids
  • Ammonia/amines– To form a-amino acids, e.g., aminoacetic acid, phenylglycine
  • Alkali cyanides– To form cyanoacetic acid and from this by saponification malonic acid
  • Alkali hydrogen sulfide– To form thioglycolic acid
  • Phenols– To form phenoxyacetic acid or PFA- coated equipment will withstand hot aqueous MCAA solutions. Titanium is suitable at temperatures below 90°C (194°F). Steel lined with stainless steel (316 ℓ) or rubber (natural or synthetic) can withstand aqueous solutions of MCAA only at temperatures below 40°C (118°F). Polypropylene and polyethylene are acceptable for use within their service temperature ranges.0.01 %if stored at 20°C (68°F)0.15%if stored at 50°C (122°F)1.00%if stored at 70°C (158°F) For detailed information, refer to the addendum to the MaterialSafety Data Sheet – Recommended Safe Handling Practices.